Ubushinwa buturiritse kunganda z'abagore - Uruganda rutanga ikirango cyihariye cyo gukuramo ifu reishi, ganoderma lucidum, Lingzhi - Johncan Ibihumyo

Imbonerahamwe

Ibisobanuro

Ibisobanuro

Ibihumyo biratangaje kubwinshi butandukanye - molekulire - uburemere bwa polysaccharide yubaka bakora, kandi bioactive polyglycans iboneka mubice byose by ibihumyo. Polysaccharide yerekana imiterere itandukanye ya biologiya macromolecules ifite ubugari - butandukanye bwimiterere ya physiochemiki. Polysaccharide zitandukanye zavanywe mumubiri wimbuto, spore, na mycelia ya lingzhi; bikozwe na fungal mycelia yatewe muri fermenters kandi irashobora gutandukana mubisukari byabo hamwe na peptide hamwe nuburemere bwa molekile (urugero, ganoderans A, B, na C). G. lucidum polysaccharide (GL - PSs) bivugwa ko igaragaza ibintu byinshi bya bioactivities. Polysaccharide isanzwe iboneka mubihumyo ikuramo amazi ashyushye hagakurikiraho imvura hamwe na Ethanol cyangwa gutandukana kwa membrane.

Isesengura ryuburyo bwa GL - PSs ryerekana ko glucose aribintu byingenzi bigize isukari. Nyamara, GL - PSs ni heteropolymers kandi irashobora kandi kuba irimo xylose, mannose, galactose, na fucose muburyo butandukanye, harimo 1-3, 1-4, na 1-6 - bihujwe β na α - D (cyangwa L) - insimburangingo.

Guhindura amashami nibiranga solubilité bivugwa ko bigira ingaruka kumiterere ya antitumorigenic yiyi polysaccharide. Ibihumyo kandi bigizwe na matrix ya chitine ya polysaccharide, ikaba idashobora kwangirika cyane numubiri wumuntu kandi ikaba ifite uruhare runini mubukomere bwumubiri bwibihumyo. Imyiteguro myinshi itunganijwe ya polysaccharide yakuwe muri G. lucidum ubu igurishwa nkuko byarangiye - the - kwivuza.

Terpène ni urwego rwibintu bisanzwe biboneka bifite skelet ya karubone igizwe nigice kimwe cyangwa byinshi bya isoprene C5. Ingero za terpene ni menthol (monoterpene) na β - karotene (tetraterpene). Benshi ni alkenes, nubwo zimwe zirimo andi matsinda akora, kandi menshi ni cycle.

Triterpène ni subassass ya terpène kandi ifite skeleton yibanze ya C30. Muri rusange, triterpenoide ifite uburemere bwa molekuline iri hagati ya 400 na 600 kDa kandi imiterere yimiti iragoye kandi oxyde cyane.

Muri G. lucidum, imiterere yimiti ya triterpène ishingiye kuri lanostane, ikaba metabolite ya lanosterol, biosynthesis ikaba ishingiye ku kuzenguruka kwa squalene. Gukuramo triterpène mubisanzwe bikorwa hakoreshejwe umusemburo wa Ethanol. Ibikuramo birashobora kurushaho kwezwa nuburyo butandukanye bwo gutandukana, harimo ibisanzwe nibisubira inyuma - icyiciro HPLC.

Triterpène ya mbere yitandukanije na G. lucidum ni acide ganoderic A na B, zagaragajwe na Kubota n'abandi. (1982). Kuva icyo gihe, byavuzwe ko triterpène zirenga 100 zifite imiti izwi hamwe n’imiterere ya molekile byagaragaye muri G. lucidum. Muri bo, abarenga 50 wasangaga ari shyashya kandi idasanzwe kuri iki gihumyo. Umubare munini ni acide ganoderic na lucidenic, ariko izindi triterpène nka ganoderal, ganoderiol, na acide ganodermic nazo zamenyekanye (Nishitoba et 1984; Sato et 1986; Budavari 1989; Gonzalez et 1999; Ma et al. . 2002; Akihisa n'abandi; Zhou n'abandi 2007;

G. lucidum bigaragara ko ikungahaye kuri triterpène, kandi iki cyiciro cyimvange nicyo gitanga ibyatsi uburyohe bwacyo kandi, byizerwa, kibaha inyungu zitandukanye mubuzima, nka lipide - kugabanya n'ingaruka za dant. Nyamara, ibirimo triterpene biratandukanye mubice bitandukanye no gukura kwigihumyo. Umwirondoro wa triterpène zitandukanye muri G. lucidum urashobora gukoreshwa mugutandukanya iyi fungus yimiti nandi moko ajyanye na tagisi, kandi irashobora kuba ibimenyetso bifatika byerekana ibyiciro. Ibirimo bya triterpene birashobora kandi gukoreshwa nkigipimo cyubwiza bwintangarugero za ganoderma zitandukanye