Cordyceps Sinensis Mycelium (CS-4)

Botanical name – Ophiocordyceps sinensis (Paecilomyces hepiali)

Chinese name – Dong Chong Xia Cao

Part used -Fungus mycelia (Solid Status Fermentation / Submerged Fermentation)

Strain name – Paecilomyces hepiali

After Reishi, Species of Cordyceps is the second most highly regarded mushroom in the Chinese materia medica, wild-harvested material fetching a high price and being a significant contributor to the economy of people living on the Tibetan plateau.

However, its use as a popular medicine is limited due to difficulties in the mass gathering of natural CS. And overharvesting has made it endangered, and until recently, it was impossible to artificially cultivate due to the difficult growth conditions.

Paecilomyces hepiali is an endoparasitic fungus that commonly exists in the natural Cordyceps sinensis.

The mycelial cultured CS mycelia (Paecilomyces hepiali) products include strong bioactive substances, such as nucleosides and polysaccharides, which are part of the bioactive substances of natural CS.

Thus, it has been recognized that the bioactivities of mycelial cultured CS are very similar to those of natural Cordyceps.


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In general, the Paecilomyces hepiali (P. hepiali) that is commonly included in natural CS from Tibet is known as an endoparasitic fungus. The genome sequence of P. hepiali is the medical compound produced using fungi, and there are some trials where it is being applied and developed in different fields. The main components of CS, such as polysaccharides, adenosine, cordycepic acid, nucleosides, and ergosterol, are known to be important bioactive substances with medical relevance.

Cordyceps Sinensis vs Militaris: Comparing the Benefits

The two species of Cordyceps are so similar in properties that they share many of the same uses and benefits. However, there are some differences in chemical composition, and thus they do present slightly different degrees of similar benefits. The main difference between Cordyceps sinensis fungus (cultured mycelium Paecilomyces hepiali) and Cordyceps militaris is in the concentrations of 2 compounds: adenosine and cordycepin. Studies have shown that Cordyceps sinensis contains more adenosine than Cordyceps militaris, but no cordycepin.

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